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NFL 2021: Week 2 betting guide, odds, more

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There were plenty of bettors out there who were probably pulling their hair out after an unpredictable and dizzying Week 1 of NFL action to open up the 2021 season.

The first week of the campaign is always the toughest to gauge, and the hope is that the sailing is a bit smoother after teams tipped their initial hands.

Of course, it's a nice theory, in concept. Here is what the Week 2 slate of games looks like for those looking to throw their hats in the gambling circle yet again.

All odds are courtesy of DraftKings.

New Orleans Saints (-3.5) at Carolina Panthers

Total points over 45: -105

Total points under 45: -115

Saints Moneyline: -180

Panthers Moneyline: +155

Cincinnati Bengals at Chicago Bears (-2.5)

Total points over/under 45: -110

Bengals Moneyline: +125

Bears Moneyline: -145

Houston Texans at Cleveland Browns (-12.5)

Total points over/under 47.5: -110

Texans Moneyline: +410

Browns Moneyline: -575

Los Angeles Rams (-3.5) at Indianapolis Colts

Total points over/under 48.5: -110

Rams Moneyline: -195

Colts Moneyline: +165

Denver Broncos (-6) at Jacksonville Jaguars

Total points over/under 45: -110

Broncos Moneyline: -275

Jaguars Moneyline: +220

Buffalo Bills (-3.5) at Miami Dolphins

Total points over/under 47.5: -110

Bills Moneyline: -190

Dolphins Moneyline: +160

New England Patriots (-6) at New York Jets

Total points over 43: -105

Total points under 43: -115

Patriots Moneyline: -255

Jets Moneyline: +205

San Francisco 49ers (-3) at Philadelphia Eagles

Total points over 50: -105

Total points under 50: -115

49ers Moneyline: -155

Eagles Moneyline: +135

Las Vegas Raiders at Pittsburgh Steelers (-6.5)

Total points over/under 47: -110

Raiders Moneyline: +215

Steelers Moneyline: -265

Minnesota Vikings at Arizona Cardinals (-3.5)

Total points over/under 50.5: -110

Vikings Moneyline: +160

Steelers Moneyline: -190

Atlanta Falcons at Tampa Bay Buccaneers (-12.5)

Total points over/under 52: -110

Falcons Moneyline: +550

Buccaneers Moneyline: -800

Dallas Cowboys at Los Angeles Chargers (-3.5)

Total points over 55: -115

Total points under 55: -105

Cowboys Moneyline: +165

Chargers Moneyline: -195

Tennessee Titans at Seattle Seahawks (-6)

Total points over 54: -115

Total points under 54: -105

Titans Moneyline: +225

Seahawks Moneyline: -280

Kansas City Chiefs (-4) at Baltimore Ravens

Total points over/under 54.5: -110

Chiefs Moneyline: -220

Ravens Moneyline: +180